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[17] [18] During injection: Relax the muscles at the injection sitetension increases pain perception

We previously discovered that, regardless of its activation state, D2R can enhance the membrane expression of DAT and consequently DAT-mediated reuptake of dopamine through their direct protein-protein interaction [23]

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This review synthesizes evidence from peer-reviewed journals published between 2020 and 2026, prioritizing systematic reviews, meta-analyses, and clinical trials